You would have to modify the field in the Settings Manager through script. This is generally true for any such field you want to change mid-game: right-click the field's label and you'll be able to copy an API reference to it to the text buffer. The click marker field is called clickPrefab, and can be changed via:
AC.KickStarter.settingsManager.clickPrefab = myNewPrefab; // Change to myNewPrefab
AC.KickStarter.settingsManager.clickPrefab = null; // Change to null (remove)
You can place these lines in your own scripts (I recommend the Start functions of C# scripts) to have them run when each scene begins.
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